Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR003002 7TM chemoreceptor, subfamily 1	619	722	21	IPR017452 GPCR, rhodopsin-like superfamily	79	84
2	IPR001810 Cyclin-like F-box	398	1251	22	IPR001128 Cytochrome P450	77	1628
3	IPR000719 Protein kinase, core	381	6862	23	IPR002048 Calcium-binding EF-hand	73	948
4	IPR002651 Protein of unknown function DUF32	225	281	24	IPR000324 Vitamin D receptor	73	2010
5	IPR000536 Nuclear hormone receptor, ligand-binding, core	207	2093	25	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	72	123
6	IPR001304 C-type lectin	192	758	26	IPR001806 Ras GTPase	72	1117
7	IPR000276 GPCR, rhodopsin-like	185	1917	27	IPR008166 Protein of unknown function DUF23	67	70
8	IPR007087 Zinc finger, C2H2-type	166	2193	28	IPR001534 Transthyretin-like	63	76
9	IPR002486 Nematode cuticle collagen, N-terminal	147	604	29	IPR004843 Metallophosphoesterase	61	478
10	IPR000210 BTB/POZ-like	137	1402	30	IPR002656 Acyltransferase 3	61	76
11	IPR001841 Zinc finger, RING-type	125	563	31	IPR000494 EGF receptor, L domain	60	165
12	IPR001680 WD40 repeat	125	2681	32	IPR000742 EGF-like, type 3	60	1509
13	IPR010726 Protein of unknown function DUF1300	120	230	33	IPR004151 C. elegans Sre G protein-coupled chemoreceptor	54	56
14	IPR000535 Major sperm protein	110	234	34	IPR002900 Protein of unknown function DUF38, Caenorhabditis species	53	66
15	IPR000504 RNA recognition motif, RNP-1	101	1473	35	IPR001611 Leucine-rich repeat	52	983
16	IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type	98	1193	36	IPR000859 CUB	50	584
17	IPR001356 Homeobox	87	693	37	IPR002110 Ankyrin	49	1137
18	IPR007114 Major facilitator superfamily	85	249	38	IPR003366 CUB-like region	49	63
19	IPR003582 Metridin-like ShK toxin	80	473	39	IPR004045 Glutathione S-transferase, N-terminal	48	121
20	IPR002198 Short-chain dehydrogenase/reductase SDR	79	941	40	IPR006583 CW	48	100

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